The upcoming ASGARD version 1.5 comes with a IOC management section in which you can manage your own set of IOCs in text files, YARA and Sigma rules.
You can then select each of the folders when creating a new scan run with THOR or SPARK. Selecting one of these folders will not include the sub folders.
You can schedule and run scans with different IOC, Sigma and YARA rule sets. You can review the included custom signatures in the scan details.
The following features are not yet implemented in v1.5 but on the roadmap for ASGARD v1.6:
- Signature verification
- Exclude the standard rule set (shipped with THOR and SPARK)